Two Compartment Model


Compartmental models are used to study the fate of a drug after it enters the body. Each compartment is an idealized volume containing the drug or chemical under study and the model represents the movement of drug between compartments. The body is divided into compartments representing regions the drug enters; some regions consist of a single anatomical organ such as the liver, while others are spread through the body, such as the volume of the circulation. The example below is a highly simplified two-compartment representation of the body, lumping all the plasma volume into the left compartment (blue) and all the extra-vascular tissue into the right compartment (green). At the start of the simulation, a dose of drug is added to the plasma compartment. During the simulation, the drug flows to the tissue compartment and is also removed (excreted) from the plasma. (Click to see: Documentation for The Two Compartment Model)


Initial Conc:

Run / Reset:
Elim Rate Coef:
Coupling Rate:
      Simulation Resources, Inc.